GROWTH AND SPREAD OF CAUSATIVE AGENT OF CREUTZFELDT-JAKOB DISEASE IN INTRAPERITONEALLY INFECTED MICE
نویسندگان
چکیده
منابع مشابه
Creutzfeldt-Jakob disease: A case report
Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...
متن کاملBlood Transfusion and Spread of Variant Creutzfeldt-Jakob Disease
Variant Creutzfeldt-Jakob disease (vCJD) may be transmissible by blood. To prevent secondary transmission through blood components, several countries have started to exclude as donors persons who have received a blood transfusion. We investigated the effectiveness of this measure by using a dynamic age-structured model. It is the first such model based on epidemiologic data: 1) blood donor acti...
متن کاملGenetic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease.
The ‘‘pulvinar sign’’ on MRI brain scan is defined as hyperintensity of the posterior thalamus relative to the signal intensity of the anterior putamen. In the appropriate clinical context, the pulvinar sign and hyperintensity in the dorsomedial thalamic nuclei (the hockey stick sign) are sensitive and specific features of variant Creutzfeldt– Jakob disease (vCJD). Variant CJD is an acquired fo...
متن کاملImmortality of cell cultures derived from brains of mice and hamsters infected with Creutzfeldt-Jakob disease agent.
Isolates from six patients with Creutzfeldt-Jakob disease (CJD) were injected into various strains of hamsters and mice, and the infective agent was propagated. Serially passaged cultures were established from these CJD agent-infected brains and from uninfected control brains. All healthy cultures (21 out of 21) from CJD agent-infected brains became immortal and/or transformed. In contrast only...
متن کاملSporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease.
BACKGROUND The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. OBJECTIVE To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD). RESULTS Results of a repeate...
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ژورنال
عنوان ژورنال: Japanese Journal of Medical Science and Biology
سال: 1990
ISSN: 0021-5112,1884-2828
DOI: 10.7883/yoken1952.43.197